High-throughput clinical assay detects, quantifies SARS-CoV-2-neutralizing antibodies
ROCHESTER, Minn., September 14, 2020 – Imanis Life Sciences, LLC announced today upcoming presentations about the development and validation of IMMUNO-COV™, the first scalable, quantitative neutralizing antibody test for COVID-19. The company will present a technical overview of the assay and host a luncheon presentation at the American Society of Gene and Cell Therapy (ASGCT) COVID-19 Symposium, a virtual event that will be held September 15-16.
In contrast to other antibody tests, the IMMUNO-COV assay specifically measures antibodies in the blood that can block infection by SARS-Co-V-2, the virus that causes COVID19. One of the key ways the immune system fights a SARS-CoV-2 infection is to make a huge number of antibodies that recognize and bind to the surface of the virus in many different ways and at many different sites. Only a small subset of those antibodies — called neutralizing antibodies — can actually prevent the virus from infecting new cells.
The IMMUNO-COV test uses an innocuous virus that mimics SARS-CoV-2 and detects neutralizing antibodies in the blood that can recognize and stop the virus from infecting new cells. Neutralizing antibodies are detectable in the blood typically 14 days after the onset of infection and their levels vary widely from person to person.
Imanis Life Sciences, under a commercial arrangement with Vyriad, is performing the IMMUNO COV assay in its CLIA-certified laboratory. Mayo Clinic has licensed IMMUNO-COV for evaluating donors in the national COVID-19 convalescing plasma study. Applications for the IMMUNO-COV assay include:
Rianna Vandergaast, Ph.D., the lead IMMUNO-COV scientist at Imanis Life Sciences, will give both presentations at the ASGCT COVID-19 Symposium.
12:00pm-1:00pm central time, Tuesday, September 15
IMMUNO-COVTM: An Antibody Test for COVID-19-Neutralizing Antibodies This luncheon presentation will provide technical information about the assay and focus on its significance, potential applications and ongoing assay research and improvements.
3:48pm-4:00pm central time, Wednesday, September 16
Development and Validation of a High-Throughput Clinical Assay for Detecting SARS-CoV-2- Neutralizing Antibodies.
This is 10-minute technical overview of the development and validation of IMMUNO-COV, as well as further assay development
To attend the free virtual conference, register here.
A recording of Dr. Vandergaast’s presentations will be available on the ASGCT website for 30 days following the symposium.
IMMUNO-COV is a product of Vyriad, Inc., developed in collaboration with its affiliate Imanis Life Sciences, Regeneron and Mayo Clinic.
Imanis Life Sciences is a leading provider of products and services to accelerate development of viro-immuno-oncology drugs. Our mission is to advance pharmacokinetics and imaging, promote widespread adoption of noninvasive in vivo imaging in preclinical and clinical research. Our team of dedicated and passionate scientists (PhD, MSc, BSc) works closely with clients to facilitate their research, from study design, custom products, and consultation. . For more information, visit www.imanislife.com.